The National Agency for Science and Engineering Infrastructure (NASENI) was established in 1992 by the Federal Government of the recommendations of the White Paper Committee on the 1991 Report of a 150 member National Committee on Engineering Infrastructure comprising Scientists, Engineers, Administrators, Federal and State Civil Servants, Economists, Lawyers, Bankers and Industrialists.

Dr. Mohammed Sani Haruna is the Executive Vice Chairman and Chief Executive of the Agency with headquarters in Abuja, Nigeria.The President Goodluck approved the reconstitution of the governing board of the National Agency for Science and Engineering Infrastructure (NASENI) with himself as the chairman. This was announced on 26th April 2013 in a statement signed by the Secretary to the Government of the Federation (SGF).

The mandate of NASENI is specifically in the area of Capital goods, research, production and reverse engineering. NASENI, by its mandate and scope of operation is the Nigerian only purpose built Agency designed to conduct developmental work in the areas of manufacturing and as such, it is capable of coordinating the proliferation of technologies developed either within or outside of its Centers including patents obtained. Technologies developed in the areas of spares, components and systems engineering are to be transferred to Entrepreneurs for the production of goods and services. Nigeria can have the benefit of a rapid technological development by strengthening NASENI.

The mission of NASENI is to establish and nurture appropriate and dynamic Science and Engineering Infrastructure-base for achieving home-initiated and home-sustained industrialization through the development of relevant processes, capital goods and equipment necessary for job creation, national economic well-being and progress. A vision is, therefore, set to create an enabling knowledge-driven environment for local mass-production of standard parts, goods and services required for the Nation's Technology Advancement.